Linear energy transfer (LET) spectroscopy and relative biological effect estimation by SiC-based dosimeter at clinical carbon-beam cancer therapy field

Abstract A radiation-tolerant silicon carbide (SiC) based dosimeter was developed for the measurement of linear energy transfer (LET) distributions along Bragg curve pristine and spread-out peak (SOBP) clinical carbon beam. Since conventional ionized chamber is not suitable effective LET measurement, several energy-dispersive dosimeters are being tested in field. While most detector lacks radiation hardness against beam, we have utilized wide-bandgap semiconductors SiC with different epitaxial layers from 25, 69, 170 μm as a field at Gunma University Heavy Ion Medical Center (GHMC). spectra were obtained only beams an 290 MeV/n but also SOBP conditions. It confirmed through changes distribution, primally carbons fragments identified, those depositions successfully by fabricated dosimeter. The distribution relative biological effectiveness (RBE) estimated estimation models. Results suggested that SiC-based successful detailed characterization therapy